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In the Early Middle Ages, on the western side of Caesar's Forum to the left of S. Adriano (Curia Senatus), a single-nave church was inserted into the walls of the Late Antique secretarium, which also preserved parts of an ancient triumphal arch and various reliefs with triumphal themes. The apse was decorated with a mosaic from the second half of the 7th century with an enthroned Madonna between donor popes. The later Baroque building (SS. Luca and Martina) has a throne in its crypt, composed of early medieval elements probably from S. Martina. A marble epigraph in the right arm of the transept of the present church recalls the consecration of an altar in 1256 by Pope Alexander IV, the date that the transformation of the presbytery with the addition of a ciborium is assumed to have taken place.